Patrick Taylor Jr. is set to make a significant impact for the San Francisco 49ers after a challenging journey in the NFL. Overcoming a Lisfranc injury in college and being undrafted, he has worked hard to earn his place on the team.

Now in his fourth year, Taylor is poised to possibly start against the Miami Dolphins, stepping up due to injuries in the running back lineup. His dedication and experience with the Green Bay Packers have prepared him for this moment.

The upcoming clash between the Miami Dolphins and San Francisco 49ers is pivotal for both teams, each struggling with a 6-8 record and slim playoff chances. This season has been a letdown for both franchises, especially after the Dolphins' recent playoff appearances and the 49ers' back-to-back NFC Championship and Super Bowl runs.

Contract disputes and injuries have plagued both teams, with the 49ers particularly suffering from a lack of key players. Their struggle to win close games has further compounded their disappointment, making them the frontrunners for the most disappointing team this season.

San Francisco 49ers rookie running back Isaac Guerendo is likely to miss the upcoming game against the Miami Dolphins due to a hamstring injury. This injury follows a series of setbacks for the team's running backs, including Christian McCaffrey and Jordan Mason, who are out for the season.

Head coach Kyle Shanahan did not disclose the injury during a previous conference call, but sources indicate Guerendo's status is dire. Patrick Taylor Jr. is expected to step in as the primary running back, with Israel Abanikanda and Ke'Shawn Vaughn as potential options.

Isaac Guerendo, the San Francisco 49ers' running back, is facing a hamstring injury that may prevent him from playing against the Miami Dolphins. This season has been challenging for the 49ers' backfield, with key players like Christian McCaffrey, Jordan Mason, and Elijah Mitchell suffering season-ending injuries.

With Guerendo's 381 rushing yards and four touchdowns, he has stepped up as a leading option. Additionally, left tackle Trent Williams is also likely to miss the game due to an ankle injury, raising concerns for the team's offensive line.

The 49ers currently hold a 6-8 record and remain in contention for a playoff spot, but they must win their remaining games and rely on outside help to secure a postseason berth.

The San Francisco 49ers are facing yet another setback with running back Isaac Guerendo likely out for their upcoming game against the Miami Dolphins due to a hamstring injury.

This adds to the team's woes, having already lost key players like Christian McCaffrey, Jordan Mason, and Elijah Mitchell to season-ending injuries. Despite these challenges, head coach Kyle Shanahan has managed to keep the offense productive.

With Guerendo sidelined, Patrick Taylor Jr. is expected to step up, although he has seen limited action this season. The 49ers, currently struggling at 6-8, still hold onto slim playoff hopes but will need a strong performance against Miami to keep those aspirations alive.